I'm running OSX 10.6.8 (SnowLeopard) on a macbook, model MacBook2,1. Thus the default onboard sound hardware is in use. I play the game since about January and the issue is present ever since; I can't judge the time before that.
Anyhow, the issue only appears with EL, other programmes don't quite have this issue like for video or audio playback or streaming nor do I see that when I play other games (mostly OpenTTD). Still, it may be some issue with the audio drivers per se as sometimes it has issues with video streaming; but it still doesn't crash the browser (FF) then but just leads to somewhat scrambled output.